Curriculum

The draft curriculum (still evolving):

1. Curriculum Aims, Goals, and Objectives

  • Aim: To provide a comprehensive understanding of the pharmaceutical pathway from molecule to drug, emphasizing the importance of interdisciplinary collaboration and ethical considerations in the drug development process.
  • Goals: Equip learners with the knowledge, skills, and competencies necessary to effectively contribute to various stages of drug development.
  • Objectives: Organized according to Bloom’s taxonomy, ranging from basic knowledge and understanding to the ability to apply, analyze, evaluate, and create within the context of the pharmaceutical pathway.

2. Content

  • Detailed exploration of the main steps of the pharmaceutical pathway, key terms, and concepts.
  • Overview of bioinformatics tools, databases, and their applications in drug development.
  • Case studies highlighting the role of interdisciplinary collaboration and regulatory considerations.

3. Learning Experiences

  • Interactive modules and simulations for applying bioinformatics tools in drug candidate research.
  • Group projects and presentations to demonstrate the pathway of a drug from molecule to drug, incorporating interdisciplinary perspectives.
  • Case study analyses to understand the complexities and challenges of drug development.

4. Teaching Strategies

  • Use of diverse didactical approaches tailored to different learning objectives, such as lecture-based learning for knowledge acquisition, problem-based learning for application and analysis, blended learning with online video lectures, and project-based learning for evaluation and creation activities.
  • Incorporation of guest lectures from industry professionals to provide real-world insights and reinforce the importance of interdisciplinary collaboration.

5. Assessment and Evaluation

  • Quizzes and exams to assess knowledge and understanding of drug development steps and key terms.
  • Practical assignments using bioinformatics tools to apply theoretical knowledge.
  • Group projects evaluating the impact of regulatory and ethical considerations, and the effectiveness of interdisciplinary collaboration.

6. Resources

  • Access to bioinformatics databases and software for practical exercises.
  • Recommended readings and online resources covering each step of the drug development pathway, interdisciplinary collaboration, and ethical considerations.

7. Implementation Plan

  • A structured timeline that progressively builds from foundational knowledge to more complex analysis and creative problem-solving.
  • Allocation of modules or units corresponding to each domain of Bloom’s taxonomy, ensuring a logical progression that facilitates deep learning.

8. Feedback and Revision

  • Regular formative feedback mechanisms through quizzes, instructor feedback on assignments, and peer reviews.
  • Summative feedback at the end of the course through course evaluations and reflection essays to assess how well the learning objectives were met and identify areas for improvement.

 

 

The table below integrates the curriculum elements of the face to face module and additional project outputs.

Face-to-face Course Modules Slidesets Supporting Materials QR Book chapter Lab guide Ecourse module
DAY 1
08:30-09:00 Opening-Registration-Pretest
09:00-09:50 Introduction and icebreaking
10:00-10:50 Discovery 1: Molecules 20-30 slides 2 D modelling game Yes Scenario Yes
11:00-11:50 Discovery 2: Bioinformatics 20-30 slides sample applications Yes Yes
12:00-12:50 Lunch Break Yes
13:00-13:50 Research 1: Preclinical drug studies 20-30 slides 3 D modelling game Yes Yes
14:00-14:30 Research 2: Cell culture, Xcelligence analysis 20-30 slides Video/Application Yes Lab guide (SOP format) Yes
14:30-15:10 Research 3 - Recombinant Protein Production, Purification And   Characterization 20-30 slides Video/Application Yes Lab guide (SOP format) Yes
15:10-16:10 Research 4 - Bioinformatics & Pharmaco-Genomics 20-30 slides sample applications Yes Lab guide (SOP format) Yes
16:10-16:50 Research 5 - Nanoparticles, drug release 20-30 slides Video/Candidate nanoparticle models with 3D printing Yes Lab guide (SOP format) Yes
16:50-17:10 Research 6 - In vivo tests and GLP 20-30 slides Video/Application Yes Lab guide (SOP format) Yes
17:10-17:50 Debrief of day 1
Day 2
08:30-09:00 Synthesis of the Day 1
09:00-09:50 Development (Clinical trials and GCP) 20-30 slides Video/Application Yes Yes
10:00-10:50 Registration (Technical requirements, Pharmacopea, Licencing and   Patenting) 20-30 slides Sample of CTD file Yes Yes
11:00-11:50 Manufacturing and Quality (Lab Safety, GMP) 20-30 slides Video/Application Yes Yes
12:00-12:50 Lunch Break Yes
13:00-13:50 Delivery (Compliance, delivery, pharmocovigilens, survey) 20-30 slides Video/Application Yes Yes
14:00-14:50 Case study: Thalidomid Disaster 10-15 slides Video/(Talidomide and comic book)
15:00-15:50 Post test, evaluation, project outputs
16:00-16:50 Closing and certification
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